Ru/ceria-catalyzed direct formylation of amines and CO to produce formamides

Column: Research    Tag: Acid-base catalysis


We herein report a new strategy of directly converting amines and CO to formamides with 100% atom utilization efficiency. It is suitable for up to 25 amine substrates with no additives. Ru/ceria is found to be an excellent catalyst for this reaction due the efficient co-activation of CO and amine on Ru species.